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Practical guidance on laboratory quality, process improvement and operational management written for the people running diagnostic labs.

AyusLab visual showing a critical laboratory result moving through recipient verification, communication and read-back, acknowledgement, escalation and documented closure.

Laboratory Quality and Compliance· ·8 min read

Critical result communication as a closed loop process

Critical result communication ensures urgent laboratory results reach the correct authorised person accurately and are acknowledged. A closed-loop process includes communication, read-back, documentation, and escalation when contact or acknowledgement fails. Clear procedures and monitoring help laboratories improve patient safety and ensure reliable critical-result reporting.

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 AyusLab visual showing a current laboratory result compared with a previous result, creating a delta flag that leads to contextual review and authorised release.

Laboratory Quality and Compliance· ·7 min read

Delta checks in laboratory medicine

Delta checks compare a patient’s current and previous results to identify unexpected changes for review. They help detect possible specimen, analytical, identification, or reporting issues without assuming the result is wrong. Proper validation, documentation, and professional review are essential for using delta checks effectively.

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AyusLab quality indicator visual connecting pre-analytical, analytical and post-analytical measures with definitions, trends, investigation and improvement.

Laboratory Quality and Compliance· ·8 min read

Practical quality indicators for diagnostic laboratories

Quality indicators help laboratories monitor important processes, identify problems, and measure improvement. They cover pre-analytical, analytical, and post-analytical activities with clearly defined measures and responsibilities. Regular trend review helps laboratories investigate issues, take corrective action, and improve overall quality.

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Controlled laboratory response from an unacceptable QC signal through containment, investigation, verification, patient-result assessment and authorised recovery.

Laboratory Quality and Compliance· ·8 min read

What laboratories should do when QC goes out of control

When QC becomes unacceptable, laboratories must contain, investigate, correct, verify, assess patient impact, and authorise return to routine work. A failed QC does not automatically mean every patient result is wrong—it signals that the analytical system requires documented review and evidence of recovery. A LIMS can support traceability, alerts, corrective-action records, result review, and audit history, while professional judgement remains essential for investigation and patient-result decisions.

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LJ Chart

Laboratory Quality and Compliance· ·8 min read

How to read a Levey–Jennings chart and recognise shifts and trends

A Levey–Jennings chart visually monitors QC results against the mean and standard-deviation limits to identify random variation, shifts, and trends. Approved QC rules and professional judgement are used to decide whether a result requires investigation or corrective action.

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Calibration in Diagnostic Lab

Laboratory Quality and Compliance· ·7 min read

QC, calibration and EQAS: how they work together

Calibration establishes the relationship used to produce analytical results, internal quality control (IQC) monitors ongoing stability, and external quality assessment (EQAS) provides independent comparison. Together, they provide complementary evidence of analytical performance and help laboratories identify, investigate, and address potential problems.

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Quality in Diagnostics

Laboratory Quality and Compliance· ·7 min read

Internal quality control in medical laboratories explained

Internal quality control (IQC) helps medical laboratories monitor the accuracy, consistency, and stability of analytical testing. It uses control materials and defined review processes to detect changes that could affect patient results and supports timely investigation and corrective action.

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